Laboratory Polarimeter, AUTOPOL® VI For Analytical Laboratories

The AUTOPOL® VI is designed as a Research Polarimeter for the most demanding analytical laboratories. If your laboratory requires the highest accuracy and must meet the most stringent compliance standards, the Autopol® VI has the measurement, temperature control, communications, and data tracking capabilities your application requires.

The Industry Standard Laboratory Polarimeter – Unmatched Accuracy: ± 0.0003° Arc

For Racemic Solutions and very low concentration samples, the Autopol® VI laboratory Polarimeter provides unmatched 4th decimal optical rotation accuracy of ±0.0003°Arc over ±1°Arc. Instrument performance for readings between -1 and 1° Arc is: Resolution ±0.0001, Reproducibility ±0.0002, and Accuracy ±0.0003.
The Autopol® V PLUS and Autopol® VI have the validation tools and features to satisfy today’s global pharmaceutical companies, including: instrument level 21CFR Part 11 compliance, NIST traceable calibration standards and a global list of installations. Rudolph Research has thousands of satisfied customers who praise the Autopol® V PLUS and Autopol® VI quality, accuracy and reproducibility.

Laboratory Polarimeter – Standard Features and Accessories

• TempTrol™ – Electronic cooling & heating from 15°-35°C
• Six Standard Wavelengths: 365nm, 405nm, 436nm, 546nm, 589nm and 633nm
• 21CFR11 Compliance: Embedded or by a separate PC
• Domestic 3-year warranty and 20-year support guarantee, International warranty varies by country
• Standard Accessories: TempTrol™ NIST Traceable Quartz Standard (3 rotation), TempTrol™ 100mm Ceramic Polarimeter Cell, TempTrol™ Temperature Validation Cell, Thermoprobe, and Built-In Sample Measurement Probe

Versatile Communication Capability

The AUTOPOL VI research polarimeter’s standard communication package includes:

• Ethernet port for Network Cable Connection
• 3 USB ports
• 2 RS 232 ports
• Easily add a USB Keyboard, Bar Code Scanner or Mouse
• 32 GB Non-Removable Compact Flash Data Storage

Allowing the capability to:

• Connect directly to Rudolph’s service department for remote testing and diagnostics via Internet connection.
• Connect to any Windows® based printer via USB or direct to the server via Windows® Print Library
• Save measurement data direct to your Network/Server

The Autopol® V PLUS and Autopol® VI  Laboratory Polarimeter Use Rudolph’s Exclusive TempTrol™ Electronic Temperature Control System

The USP <781> requires optical rotation measurements at 25°C ± .5°C (unless another temperature is specified). The (EP) European Pharmacopoeia requires optical rotation measurements made at 20° ± .5°C (unless another temperature is specified).
Whatever your temperature control needs are, the Autopol® VI and the Autopol® V PLUS’ exclusive TempTrol™ System (Patent No. 6,717,665) makes your measurement in a few minutes without a water bath or any type of water circulation.
The TempTrol™ System allows push-button temperature control of your 100mm cell, 200mm cell or Quartz Plate. Set the temperature, push “measure” and walk away. The Autopol® Laboratory Polarimeter will heat or cool to a predefined temperature and then provide you with the result all in one easy step.

Patented TempTrol™ Technology Eliminates the Need for a Water Bath. Here is How the TempTrol™ System Works:

TempTrol™ heating and cooling transfer surface in the polarimeter sample chamber

Select temperature via touch screen. Temperature selection of 20°C or 25°C shown above.
TempTrol™ cell with mating heating & cooling transfer surface manufactured with acid resistance materials: NEDOX™ and Peek™ below.

Place the TempTrol™ cell in your TempTrol™ equipped Autopol® polarimeter sample chamber to measure within ±0.2°C of the USP, EP, JP, or BP specified temperature (normally 20°C or 25°C ±0.5°C)

To Validate Temperature Performance

Rudolph provides a temperature validation cell with every TempTrol™ system. The temperature validation cell along with an optional NIST traceable Thermo Probe is designed to validate the temperature control performance of the polarimeter and cell to ±0.2°C.

cGMP/GLP Printing

Measurement reports can be saved as an Excel or PDF file and edited quickly and easily. You can import logos and print your company’s customized “C of A” directly directly from the Autopol® VI Polarimeter.

Validation and Calibration

Rudolph Research Analytical knows that you must be able to validate your laboratory polarimeter’s operating performance regularly. Therefore, the AUTOPOL® VI comes standard with the accessories, validation tool and automatic calibration functions necessary to ensure that the temperature control, temperature measurement and optical measurement processes are working accurately and reproducibly. All functions are assessed simply and conveniently through the AUTOPOL® VI liquid sealed touch screen.

Unmatched Accuracy in a Laboratory Polarimeter

For Racemic Solutions and very low concentration samples, the AUTOPOL® VI Laboratory Polarimeter provides unmatched 4th decimal Optical Rotation accuracy of ±0.0003°Arc over ±1°Arc. Instrument performance for readings between -1 and 1° Arc is: Resolution ±0.0001, Reproducibility ± 0.0002, and Accuracy ±0.0003.

Intuitive Windows® Embedded Interface

• 32 gigabytes of internal memory allow almost unlimited capacity for saving measurement data. The AUTOPOL®VI Laboratory Polarimeter is network ready and data may also be saved directly to your server or to any directory desired.
• Internet access is possible directly from the AUTOPOL® VI’s touch screen. This feature allows real time contact with Rudolph Research Analytical’s Service and Technical Support Team who can access your instrument remotely to assist in Window navigation, method setup and troubleshooting.
• Windows based navigation architecture is so intuitive that most operators will never read the manual. But should you wish to reference the manual, it is stored right on the AUTOPOL VI’s internal memory.
• Three USB ports allow quick and easy connection to a mouse, keyboard, printer, bar code scanner, or memory stick. One USB port is located on the front of the unit and two USB ports are located on the back of the unit.

Laboratory Polarimeter – Flexible Method Management

Install your own measurement methods for immediate selection of the correct method to match your most common tests. Setting up your own custom methods is as simple as filling out a few screens like the one shown to the right.

Full 21CFR Part 11 Instrument Level Compliance

The AUTOPOL VI’s 21CFR Part 11 software module is easily enabled through the user friendly touch screen. This module gives you full compliance with:

• Electronic signature
• Access levels
• Internal write protected storage
• Unique passwords
• Write protected documents sent directly to server
• Audit trail

Acid Resistance

The AUTOPOL® VI polarimeter comes standard with Rudolph’s Hastelloy™ upgrade option. This option includes a Hastelloy™ cell and Silco Steel™ cell chamber for increased resistance to acids like 6 Molar HCl.

Rudolph Research Analytical — still protecting your investment after 30 years

Today our Service Technicians have access to state of the art diagnostic tools and have a depth of knowledge that often lets them solve problems right over the phone. Our customers really appreciate the same day phone call by a real technical service person who wants to solve their problem. Our customers know that they can expect this support for many years to come as Rudolph is still repairing laboratory polarimeters which were built in the 70’s.

All Rudolph Instruments carry our exclusive 20 Commitment to service your instrument.

Rudolph Research Analytical offers a comprehensive range of Preventive Maintenance and Service Programs. Rudolph has demonstrated a commitment to its customers by keeping installed instruments operational, not only for 20 years, but in some cases for over 40 years. This long-term commitment to keeping our instruments running makes the cost of ownership, over the life of a Rudolph Laboratory Polarimeter, one of the lowest in the laboratory market segment. At the date this document was published, there is no other laboratory instrument manufacturer guaranteeing service and technical support for 20 years. View the entire 20 Service Guarantee.